Withdrawal by Substance

Kratom Withdrawal

Kratom is a plant-derived substance whose active compounds act on opioid receptors, producing effects and withdrawal that meaningfully overlap with traditional opioid withdrawal —…

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Withdrawal by Substance

Buprenorphine Implant/Injection Discontinuation

Long-acting buprenorphine formulations — the Probuphine implant and monthly injections like Sublocade or Brixadi — release medication steadily over weeks, which changes what “stopping”…

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Withdrawal by Substance

Opium and Poppy Seed Tea Withdrawal

Poppy seed tea — brewed from poppy seeds or pods containing residual opium alkaloids (morphine and codeine) — is a lesser-discussed but real source…

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Withdrawal by Substance

Carfentanil Exposure: Facts and Myths

Carfentanil is an extremely potent synthetic opioid, approved only for large-animal veterinary sedation, that has appeared in the illicit drug supply in some regions.…

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Withdrawal by Substance

Fentanyl Analog Withdrawal

Fentanyl analogs — chemically modified versions of fentanyl such as acetylfentanyl, furanylfentanyl, and others — periodically appear in the illicit drug supply, sometimes without…

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Withdrawal by Substance

Loperamide Dependence and Withdrawal

Loperamide (Imodium) is an over-the-counter anti-diarrheal that, at doses far beyond the recommended package amount, crosses into the brain enough to produce opioid-like effects…

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