Changes in libido and sexual function are common during withdrawal and can persist into early recovery — a symptom rarely discussed openly, which can make it feel more isolating than it needs to be.

Why it happens: Long-term opioid use affects hormone levels, including testosterone, in both men and women — a condition sometimes called opioid-induced androgen deficiency. Withdrawal and early recovery involve the body recalibrating this hormonal system, which takes time and can affect libido, function, and mood together.

What tends to help: Recognizing this as a physiological, common withdrawal-and-recovery effect rather than a personal or relationship problem; giving it time, since hormone levels often normalize over weeks to months; mentioning it to a doctor, especially if it persists — hormone levels can be tested, and this is a legitimate, common enough concern that a good provider won’t be surprised by the question.

A note for partners: This is a physical effect of withdrawal and recovery, not a reflection of attraction or the relationship — worth saying directly if it’s affecting a relationship during this time.

Medically reviewed by [pending]. Sources: SAMHSA TIP 63, endocrinology literature on opioid-induced hypogonadism.